Modulating Reactive Oxygen Species Production and the Src/Epidermal Growth Factor Green Tea Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Rats
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[PDF] [Full Text] [Abstract] , August 1, 2008; 52 (2): 301-307. Hypertension L. Monassier, M.-A. Laplante, F. Jaffre, P. Bousquet, L. Maroteaux and J. de Champlain Hypertrophy in Mice Serotonin 5-HT2B Receptor Blockade Prevents Reactive Oxygen Species-Induced Cardiac [PDF] [Full Text] [Abstract] , September 1, 2008; 138 (9): 1596-1601. J. Nutr. Semplicini I. Papparella, G. Ceolotto, D. Montemurro, M. Antonello, S. Garbisa, G. Rossi and A. Receptor/Akt Signaling Pathway Modulating Reactive Oxygen Species Production and the Src/Epidermal Growth Factor Green Tea Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Rats by [PDF] [Full Text] [Abstract] , January 1, 2009; 328 (1): 99-106. J. Pharmacol. Exp. Ther. L. Fan, D. Sawbridge, V. George, L. Teng, A. Bailey, I. Kitchen and J.-M. Li Activation: The Role of Nox2 Oxidase Chronic Cocaine-Induced Cardiac Oxidative Stress and Mitogen-Activated Protein Kinase [PDF] [Full Text] , February 1, 2009; 53 (2): 112-114. Hypertension M. C. Zimmerman and I. H. Zucker Targets for Neurogenic Hypertension? Mitochondrial Dysfunction and Mitochondrial-Produced Reactive Oxygen Species: New [PDF] [Full Text] [Abstract] , April 1, 2009; 296 (4): C693-C700. Am J Physiol Cell Physiol Rasmussen C. N. White, G. A. Figtree, C.-C. Liu, A. Garcia, E. J. Hamilton, K. K. M. Chia and H. H. oxidase Angiotensin II inhibits the Na+-K+ pump via PKC-dependent activation of NADPH
منابع مشابه
Green tea attenuates angiotensin II-induced cardiac hypertrophy in rats by modulating reactive oxygen species production and the Src/epidermal growth factor receptor/Akt signaling pathway.
We previously documented a clear-cut antihypertensive effect of green teat extract (GTE), which was associated with correction of endothelial dysfunction and prevention of left ventricular hypertrophy in an angiotensin II (Ang II)-dependent model of hypertension, but the molecular mechanisms remain to be defined. As several effects of Ang II involve production of reactive oxygen species (ROS) a...
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BACKGROUND Heme oxygenase-1 (HO-1) is a stress-response enzyme implicated in cardioprotection. To explore whether HO-1 has a role in cardiac remodeling response, the effect of its overexpression on angiotensin II (Ang II)-induced cardiac hypertrophy was examined. METHODS AND RESULTS HO-1 was induced in cultured rat neonatal cardiomyocytes by treatment with cobalt protoporphyrin IX (CoPPIX) or...
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Gqα signaling has been implicated in cardiac hypertrophy. In addition, angiotensin II (Ang II) was also shown to induce its hypertrophic effect through Gqα and PKCδ activation. We recently showed the role of enhanced expression of Gqα/PLCβ1 proteins in vascular smooth muscle cell (VSMC) hypertrophy, however, the role of PKCδ in VSMC hypertrophy in animal model is still lacking. The present stud...
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BACKGROUND Left ventricular hypertrophy commonly complicates chronic renal failure. We have observed that at least one pathway of left ventricular hypertrophy appears to involve signaling through reactive oxygen species (ROS). Green tea is a substance that appears to have substantial antioxidant activity, yet is safe and is currently widely used. We, therefore, studied whether green tea supplem...
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Urotensin II (U-II) is implicated in cardiomyocyte hypertrophy, which results in cardiac remodeling. We recently demonstrated that both reactive oxygen species (ROS) generation and epidermal growth factor receptor (EGFR) transactivation play critical roles in U-II signal transduction. However, the detailed intracellular mechanism(s) underlying cardiac hypertrophy and remodeling remain unclear. ...
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تاریخ انتشار 2006